Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
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چکیده
منابع مشابه
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
Mutations in hemojuvelin (HJV) are the most common cause of the juvenile-onset form of the iron overload disorder hereditary hemochromatosis. The discovery that HJV functions as a co-receptor for the bone morphogenetic protein (BMP) family of signaling molecules helped to identify this signaling pathway as a central regulator of the key iron hormone hepcidin in the control of systemic iron home...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2014
ISSN: 1663-9812
DOI: 10.3389/fphar.2014.00104